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Bontril

Generic Name: phendimetrazine (fen di MEH tra zeen)
Brand Names: Adipost, Anorex-SR, Appecon, Bontril PDM, Bontril Slow-Release, Melfiat, Obezine, Phendiet, Plegine, Prelu-2, Statobex

Bontril is an appetite suppressant which is prescribed for short-term use (a few weeks) as part of an overall weight reduction program that also includes dieting, exercise, and counseling. The drug is for use only by excessively overweight individuals ( BMI > 27 or 30 depending on other health issues) who have a condition, such as diabetes, high blood pressure, or high cholesterol, that could lead to serious medical problems.

While diet pills would appear to be the answer to achieving to a leaner, healthier body, they need to be used in conjunction with a healthier eating / exercise plan if you plan to keep the lost weight from returning after you stop taking the diet pills. If bad eating and exercise habits are not changed while using Bontril, or any other diet pill, the weight lost while using the diet pill will most likely be regained once you stop taking Bontril.

How do I use Bontril?

Take Bontril exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass of water. Bontril ( Phendimetrazine ) is usually taken once a day (sustained release formula) or two to three times daily (immediate-release formula) before meals on an empty stomach. The sustained-release or long acting versions of Bontril must be swallowed whole because crushing or chewing them will destroy the long action and may cause increased side effects. You should avoid taking a dose late in the day because this medication may cause sleeplessness. Bontril is usually taken for 8 to 12 weeks and should not be used combination with other appetite suppressant medicine.

Bontril is habit forming. You can become physically and psychologically dependent on this medication, and withdrawal effects may occur if you stop taking it suddenly after several weeks of continuous use. Talk to your doctor about stopping this medication gradually.

Who should NOT take Bontril?

You cannot take Bontril ( phendimetrazine ) if you:
  • have heart disease or high blood pressure;

  • have arteriosclerosis (hardening of the arteries);

  • have glaucoma;

  • have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days; or

  • have a history of drug or alcohol abuse.

Before taking this medication, tell your doctor if you have

  • problems with your thyroid,
  • an anxiety disorder,
  • epilepsy or another seizure disorder, or
  • diabetes.
You may not be able to take Bontril ( phendimetrazine ), or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Due to the fact that the side effects to fetuses and babies are unknown and could be potentially very dangerous, it is NOT recommended to use Bontril while you are pregnant or breastfeeding.


What are the side effects of Bontril?

If you experience any of the symptoms below which are marked in red, discontinue using Bontril immediately and call your doctor.

The most common Bontril side effects include but are not limited to:

Cardiovascular Side Effects:
Irregular heartbeat, very high blood pressure

Central Nervous System Side Effects:
Hallucinations, abnormal behavior, confusion, restlessness, tremors, nervousness, anxiety, headache, dizziness, insomnia

Gastrointestinal Side Effects:
Dry mouth, an unpleasant taste in your mouth, diarrhea, constipation

Allergic Side Effects
Difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives

Endocrine Side Effects:
Impotence or changes in your sex drive.


Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Bontril Dangers

Use caution when driving, operating machinery, or performing other hazardous activities. Bontril may cause dizziness, blurred vision, or restlessness, and it may hide the symptoms of extreme tiredness. If you experience these effects, avoid hazardous activities.

Do not crush, chew, or open any "once-daily" phendimetrazine tablets or capsules. Swallow them whole. Failure to follow this direction could lead to very serious health issues.

Bontril Drug Interactions

You cannot take phendimetrazine if you have taken a monoamine oxidase inhibitor (MAOI) in the last 14 days.

Changes in insulin and other diabetes drug therapies may be necessary during treatment with Bontril.

Bontril may reduce the effects of guanethidine (Ismelin). This could lead to an increase in blood pressure. Tell your doctor if you are taking guanethidine.

Before taking this medication, tell your doctor if you are taking a tricyclic antidepressant. These drugs may decrease the effects of Bontril.


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Disclaimer: The information presented on this site is for informational purposes ONLY and should never replace the expertise of a qualified medical professional. The information presented here is meant to be a stepping stone to help you with learning about the various diet pills available and is by no means meant to be a replacement for more qualified and current information your doctor may have. The drug interactions listed here are not comprehensive. If you don't see a particular interaction is not listed, does not mean that there isn't one. Contact your doctor to make sure other prescriptions or herbal remedies will not interact adversely with a diet pill prescription. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. We are neither liable nor responsible for any loss, claim, damage, or lawsuit resulting from any drug use.